Фенотип бронхиальной астмы с фиксированной обструкцией
Характерной особенностью бронхиальной астмы (БА) является обратимая обструкция воздушного потока, которая быстро устраняется бронхолитиками короткого действия. Однако неполная обратимость (результаты спирометрии не нормализуются, несмотря на лечение), которая также называется фиксированной бронхиальной обструкцией (ФБО), встречается у 60% пациентов с тяжелым течением БА. Больные БА с ФБО – это особая когорта, характеризующаяся тяжелым течением заболевания, торпидностью к терапии высокими дозами ингаляционных кортикостероидов. Фенотип БА с ФБО требует дополнительного изучения для определения объема и выбора терапии.Костина Е.М., Трушина Е.Ю., Типикин В.А., Орлова Е.А.
Ключевые слова
бронхиальная астма
фенотип
фиксированная бронхиальная обструкция
Список литературы
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Об авторах / Для корреспонденции
Автор для связи: Елена Юрьевна Трушина, к.м.н., доцент кафедры пульмонологии и фтизиатрии, Пензенский институт усовершенствования врачей – филиал ФГБОУ ДПО РМАНПО Минздрава России, Пенза, Россия, trushina.lena@mail.ru
ORCID / eLibrary SPIN:
Е.М. Костина (E.M. Kostina), ORCID: http://orcid.org/0000-0003-1797-8040; eLibrary SPIN: 2111-8827
Е.Ю. Трушина (E.Yu. Trushina), ORCID: http://orcid.org/0000-0001-5673-9195; eLibrary SPIN: 2164-6580
В.А. Типикин (V.A. Tipikin), ORCID: http://orcid.org/0009-0000-0990-4661; eLibrary SPIN: 7403-8592
Е.А. Орлова (E.A. Orlova), ORCID: https://orcid.org/0000-0002-3902-2018; eLibrary SPIN: 1700-4848
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